Chest Wall Tumours

Complete resection: May need to remove a length of healthy tissue around the tumour to ensure a clean resection margin.
Reconstruction: Restore the shape and function of the chest wall with autologous tissue or artificial materials, depending on the size of the defect.

• May need musculocutaneous flaps (e.g., latissimus dorsi), prosthetic meshes (e.g., PTFE) or metallic materials.
• May need rigid support (e.g., rib prosthesis) to restore structural stability.

• Neoadjuvant: Shrinks large or locally invasive tumours before operation to increase the chance of complete resection.
• Adjuvant: Reduces local recurrence risk, especially when margins are close or positive;
• Palliative: for unresectable tumours.

• Systemic regimens: Multi-agent protocols (e.g., ifosfamide plus doxorubicin) for high-grade sarcomas or metastatic disease.
• Targeted/Immunotherapy: Considered in tumours with specific molecular alterations (e.g., PD-1 inhibitors in sarcoma subtypes).