Articular Cartilage Damage
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Articular Cartilage Damage

Orthopaedics

Cartilage is a flexible, smooth connective tissue that covers the ends of bones within joints. It plays a vital role in reducing friction and absorbing shock during joint movement. Articular Cartilage Damage refers to damage or deterioration of this tissue and is commonly found in the knee, hip, shoulder, and ankle joints. Since cartilage has very limited self-repair ability, early diagnosis and treatment are crucial.

Symptoms

  • Joint pain, especially during weight-bearing or movement
  • Reduced range of motion or feeling of "locking"
  • Swelling or fluid buildup in the joint (effusion)
  • Joint instability or weakness
  • Clicking or grinding noises during movement

Causes

Sports activities, trauma, work-related injuries, repetitive wear and tear, and avulsion can all damage joint cartilage. The common causes can generally be categorized as follows:

  • Trauma: Sports injuries, falls, or vehicle accidents
  • Degeneration: Age-related wear-and-tear often associated with osteoarthritis
  • Repetitive stress or overuse: From physical labour or intense exercise
  • Post-meniscal or ligament injury: Secondary cartilage damage
  • Congenital conditions, Such as hip dysplasia or bone alignment issues

Risk Factors

  • Aging (cartilage regeneration declines over time)
  • Athletes or highly active individuals
  • Obesity (increased joint loading)
  • History of joint ligament or meniscus injuries
  • Poor biomechanics or improper footwear

Complications

  • Osteoarthritis: Progressive cartilage loss leads to bone-on-bone friction
  • Joint instability or deformity
  • Chronic pain and mobility restriction
  • Recurrent joint effusion or synovitis
  • Bone marrow edema and joint capsule degeneration

Diagnosis

  • Clinical examination and medical history: Key to understanding the injury mechanism
  • X-ray: To rule out fractures or bone spurs (cartilage itself not visible)
  • MRI scan: The gold standard for cartilage assessment, showing soft tissue and bone marrow conditions
  • Arthroscopy: A minimally invasive procedure to directly visualize and treat cartilage damage

Treatments

There are currently several treatment options for cartilage injuries. Orthopaedic surgeons will determine the treatment plan based on the type and severity of your knee joint injury. It is strongly recommended to seek early treatment, as this can help prevent the damage from spreading to surrounding healthy cartilage and further deterioration of the joint surface.

Surgical Treatments
  • Arthroscopic Chondroplasty / Debridement
    Using arthroscopy, the orthopaedic surgeon identifies and removes the damaged cartilage. This method prevents loose fragments from causing joint irritation and swelling. This "clean-up" procedure of the joint surface is called chondroplasty. While it can provide temporary pain relief, it does not repair cartilage defects.
     
  • Marrow Stimulation / Microfracture
    In some cases, microfracture surgery under arthroscopy is performed to stimulate bone marrow, inducing the release of the body’s own mesenchymal stem cells (MSCs) to repair small cartilage defects. Small surgical tools are used to drill or abrade the area beneath the cartilage defect, creating tiny fractures. Blood and marrow (containing stem cells) seep from these microfractures and form a clot that helps in cartilage regeneration. This can be highly effective in relieving symptoms in certain patients.
     
  • Osteochondral Autograft Transfer (OAT)
    In this procedure, the surgeon harvests healthy cartilage and the underlying bone from a non-weight-bearing area of the patient’s own joint and transplants it into the damaged area. This technique is suitable for defects no larger than 2.5 cm² (roughly the size of a thumbnail).
     
  • Autologous Chondrocyte Implantation (ACI)
    This method involves harvesting a small amount of healthy cartilage tissue from the patient, isolating the patient’s own chondrocytes (cartilage cells), and cultivating them in a lab over several weeks. Once sufficient cells are obtained, they are implanted into the cartilage defect. Since the patient’s own cells are used (autologous cells), there is no risk of rejection. This technique can treat small to large defects. MACI is an enhanced version of ACI.
     
  • Allograft (Donor Cartilage Transplantation)
    For large bone and cartilage defects, fresh donor cartilage and bone from cadavers may be used. The benefit of this approach is that the graft can contain both mature cartilage and bone for repair, but it carries risks such as infection and graft rejection.
     
  • Artificial Joint Replacement (for severe degeneration)
Non-Surgical Treatments
  • Rest and Load Reduction
     
  • Physiotherapy: To strengthen muscles, improve gait, and enhance joint stability
     
  • Pain Relievers and Anti-inflammatory Medications: Such as NSAIDs
     
  • Hyaluronic Acid Injections: To improve joint lubrication
     
  • Platelet-Rich Plasma (PRP) Injections: An advanced regenerative treatment commonly used in orthopaedics. It involves drawing the patient’s own blood, processing it to concentrate the platelets, and injecting it into injured or degenerative areas to promote healing and tissue repair.

FAQ

Cartilage has poor blood supply and limited self-healing ability. Most injuries will not fully recover without treatment.
Yes, particularly in athletes or those experiencing repetitive joint trauma.
Not always. Mild damage may respond to conservative treatments. Surgery is considered when symptoms are severe or joint function is impaired.
Maintain healthy weight, avoid overuse, warm up properly before exercise, and wear supportive footwear.

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